Primary intraosseous squamous cell carcinoma in pre-existing keratocystic odontogenic tumor: A case report and literature review

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Primary intraosseous squamous cell carcinoma arising from keratocystic odontogenic tumor.

Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare lesion that almost exclusively occurs in the jaws. Most PIOSCCs originate from epithelial lining of odontogenic cysts, especially from radicular, residual, and dentigerous cysts. A few cases have been shown to arise from keratocystic odontogenic tumors (KCOTs). This is a report of a case of PIOSCC that arose from an untreated kerat...

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Primary intraosseous squamous cell carcinoma of mandible: a case report

Background: Primary intraosseous squamous cell carcinoma (PIOC) of the mouth is a very rare but well-known carcinoma. It is locally invasive and its prognosis is quite poor. It may originate from the walls of an odontogenic cyst or de novo from the remnant epithelium at this region. Because the early symptoms of such malignancies are sometimes similar to those of inflammatory or periodontal dis...

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Primary intraosseous squamous cell carcinoma arising from an odontogenic keratocyst: a case report and literature review

Primary intraosseous squamous cell carcinoma (PIOSCC) derived from an odontogenic keratocyst (OKC) is a rare malignant neoplasm of the jaws, which is locally aggressive with quite poor prognosis. The incidence of carcinomas arising in odontogenic cysts was reported to be approximately 1-2/1000. The number of well-documented cases of PIOSCC ex OKC is extremely small; hence, no sufficient inciden...

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Giant Keratocystic Odontogenic Tumor: Three Cases and a Literature Review

Introduction: A keratocystic odontogenic tumor is a benign intra-bone mass originating from dental lamina or its residue. It represents 2–11% of jaw cysts, and has a slow but aggressive growth. The evaluation of molecular characteristics, immunohistochemistry, and genetic expression currently have no established classification regarding the evolution and pathophysiologic pattern of these lesion...

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Squamous cell carcinoma arising from a keratocystic odontogenic tumor: a case report

BACKGROUND The term "primary intraosseous squamous cell carcinoma" was introduced in 2005 by the World Health Organization with three subcategories. Squamous cell carcinoma arising from the lining of an odontogenic cyst is one important rare subcategory of such lesions with an incidence of 0.01 to 0.02%. Furthermore, the appearance of such malignancy in an odontogenic tumor such as keratocystic...

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ژورنال

عنوان ژورنال: Molecular and Clinical Oncology

سال: 2015

ISSN: 2049-9450,2049-9469

DOI: 10.3892/mco.2015.678